Hard-Wired to NOT Be Hard-Wired – Pat Clarkin on Our Marvelous Flexibility

  Humans are hard-wired not to be hard-wired. That phrase, drawn from Ken Weiss, is perhaps the simplest of the many ways that Patrick Clarkin tries to convey, in his wonderful post “Developmental Plasticity and the ‘Hard-Wired’ Problem,” how thoroughly entwined are genetics and experience in shaping and constantly reshaping any organism. It’s silly, in a way, to […]

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How Box Scores Are Like Gene Sequences: The Geek Path from Baseball to Bio

How is a box score like a genome sequence? This starts a wee slow, but go with it: Noted computational biologists James Fraser (UCSF) and Michael Eisen (Berkeley) explain how obsessions with baseball stats led them — and can lead others — to be data-heavy biologists. First lesson, for example: Predictions are stronger based on (open) […]

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